Italian mafia boss Bernardo Provenzano has died in a prison hospital, aged 83.
Provenzano, dubbed "The Tractor" for his ruthless trait of mowing people down, was arrested and jailed in 2006 after spending 43 years on the run.
He was suffering from bladder cancer and serious cognitive impairment and had spent the last two years in a prison hospital ward, Italian media report.
His illnesses had forced the suspension of ongoing negotiations with the state over unresolved crimes. However, even before his health declined, he had resisted any co-operation with the justice system.
The dairy farm where Provenzano's years on the run finally came to an end, and he was arrested in jeans and a pullover, an old man of 73
He was said to have joined the mafia in his late teens, after World War Two.
Once at the helm following Riina's capture, Provenzano reportedly tried to arbitrate between rival Mafia factions competing for business. He was said to have steered away from attacks on high-profile figures that had hardened public opinion against the Mafia and provoked police to respond.
In his later years, painstakingly cautious about revealing his whereabouts, Provenzano shunned the phone for hand-delivered "pizzini" notes and moved between farmhouses every two or three nights.
But in April 2006, he was arrested at a farmhouse near Corleone, his birthplace and where his wife and children lived.
Bernardo Provenzano earned the nickname The Tractor because, as an informant put it, "he mows people down".
He reportedly committed his first murder in 1958 aged 25, when Provenzano is alleged to have been one of the gunmen who helped rising mafioso Luciano Liggio murder Corleone clan head Michele Navarra, leaving Liggio as head of the family.
However, Provenzano had another side to his character.
He was a careful operator, who took few overt risks, mastered the crime empire's finances, and under whose leadership the Mafia became a less bloodthirsty, more efficient machine, commentators say.
For these reasons, he was also dubbed The Accountant.